Mark Esparza

• Eye movement disorders: smartphone recording of nystagmus and saccades
• Protein and ligand binding: contact profiling, binding pocket detection, evolutionary conservation
• Cheminformatics: molecular descriptors, structural similarity, metabolite data
• Educational software for medicine and pharmacology
• Health literacy and patient preparation for medical visits

• Doctor of Osteopathic Medicine (DO), in progress
  College of Osteopathic Medicine, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma
• Master of Science (MS) in Biomedical Sciences, in progress
  Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma
• Master of Business Administration (MBA), 2025
  Oklahoma State University, Stillwater, Oklahoma
• Bachelor of Science (BS) in Community Health, 2023
  University of Oklahoma, Norman, Oklahoma

Certificates

• Professional Certificate in Computer Science for Python Programming, HarvardX (edX)

1. Esparza, M. (2026). OcuTrace: Smartphone Oculomotor Recording for Neurology and Clinical Research [Preprint]. Zenodo. https://doi.org/10.5281/zenodo.23345364 Preprint, not peer reviewed. Proposes a smartphone platform for standardized oculomotor testing and reports synthetic validation of the browser prototype. CC BY 4.0 PDF

2. Esparza, M. (2026). SnaCleX: a browser-based structural biology workbench for protein–ligand interaction analysis, pocket prioritization, and exploratory docking [Preprint]. Zenodo. https://doi.org/10.5281/zenodo.23326777 Preprint, not peer reviewed. Describes the SnaCleX software and its benchmark on the Astex Diverse and PoseBusters sets. CC BY 4.0 PDF

In preparation

3. Esparza, M., & Rudd, K. Structured Pre-Visit Preparation for Medical Appointments: A Practical Application and the Development of a Bilingual, Accessibility-Informed Community Toolkit. Manuscript in preparation.

Peer reviewed publications will be listed here as they appear. The current list of works is also kept on ORCID and the OSU Experts Directory.

1. Esparza, M. (2026). OcuTrace: browser-based nystagmus and saccade recording from phone video (Version 0.3.0) [Computer software]. Zenodo. https://doi.org/10.5281/zenodo.23345223 Turns a phone video of the eyes into a quantitative oculomotor recording, with a standardized task battery and Eye-Tracking-BIDS export. Research prototype, not a medical device. MIT GitHub Live

2. Esparza, M. (2026). SnaCleX: a browser-based structural biology workbench for protein–ligand interaction analysis (Version 0.1.0) [Computer software]. Zenodo. https://doi.org/10.5281/zenodo.23167411 Contact profiling, pocket detection and ranking, conservation scoring, and exploratory docking from RCSB PDB structures. MIT GitHub

3. Esparza, M. (2026). Molecule Design Assistant (chemtool) (Version v1.0.0) [Computer software]. Zenodo. https://doi.org/10.5281/zenodo.23167242 Reaction balancing, analog design with property scoring, and live PubChem and HMDB lookups. Apache 2.0 GitHub

4. Esparza, M. (2026). Investment-Viability Analysis (Version v0.1.0) [Computer software]. Zenodo. https://doi.org/10.5281/zenodo.23167234 Finance metrics and a live formula Excel workbook built from SEC EDGAR filings. MIT GitHub

1. Esparza, M. (2026, October 6). Bilingual pre-visit preparation toolkit (trifold display and visit planner). Centered Around Health Fair, Tulsa, Oklahoma. English and Spanish educational materials helping patients prepare for medical appointments.